C. elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor
Gabrielle E. Giese, Melissa D. Walker, Olga Ponomarova, Hefei Zhang, Xuhang Li, Gregory Minevich, Albertha J.M. Walhout
The paper identifies two mechanisms by which vitamin B12 regulates the methionine/S-adenosylmethionine cycle in C. elegans, involving transcriptional adjustments via nuclear hormone receptors.
eLife · Oct 5, 2020Peer-reviewedSystems Biology