Gabrielle E. Giese

WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization

The paper manually annotates and visualizes metabolic pathways in C. elegans, providing pathway maps for metabolic enrichment analysis of transcriptomic data.

C. elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor

The paper identifies two mechanisms by which vitamin B12 regulates the methionine/S-adenosylmethionine cycle in C. elegans, involving transcriptional adjustments via nuclear hormone receptors.

A Persistence Detector for Metabolic Network Rewiring in an Animal

The paper identifies a persistence detector in an animal that redirects propionate breakdown to a shunt pathway when flux through the canonical pathway is perturbed.

C. elegans Multidrug Resistance Protein 5 (MRP-5) Transports Vitamin B12 from the Intestine to the Gonad to Support Embryonic Development