Author

Chance C. Sine

University of Colorado BoulderORCID 0000-0002-7184-146XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Sabrina L. SpenceriD· 2 shared Agnieszka Katarzyna WitkiewicziD· 1 shared Alexander van OudenaardeniD· 1 shared Alva BiraniD· 1 shared Anja GrothiD· 1 shared Brianna Fernandez· 1 shared Claire ArmstrongiD· 1 shared Claire BurnyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Sabrina L. SpencerORCID

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2 papers

Recent·Most cited

Cancer BiologyScience SignalingPeer-reviewedNov 25, 2025

p16 expression confers sensitivity to CDK2 inhibitors

Chance C. Sine, Lotte P. Watts, Brianna Fernandez…·Sabrina L. Spencer

The paper shows that p16 expression in ovarian cancers increases sensitivity to CDK2 inhibitors by inhibiting CDK4/6, suggesting p16 as a biomarker for CDK2 inhibitor response.

12 citationstop 3%

humanproteomics

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Cell BiologyMolecular CellPeer-reviewedNov 12, 2024

Acute multi-level response to defective de novo chromatin assembly in S-phase

Jan Dreyer, Giulia Ricci, Jeroen van den Berg…·Francesca Mattiroli

This study investigates the acute effects of CAF-1 loss on chromatin assembly during S-phase, revealing multi-level responses including replication slowdown and histone modification changes.

17 citations

humanscRNA-seq

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