Clay F. Semenkovich

This study shows that palmitoylation regulates mitochondrial transport of insulin across the endothelium, improving insulin sensitivity in insulin resistance.

This study identifies SCD as a lipid metabolic checkpoint that regulates macrophage activation and plasticity by maintaining lipid desaturation balance and preventing pro-inflammatory responses.

This study shows endothelial CEPT1 regulates hepatic MTTP activity, affecting lipid metabolism and aortic atherosclerosis.

This study investigates how insulin regulates lymphatic endothelial function through palmitoylation, identifying CD36 as a mediator of this process.

This study shows that endothelial Cept1 promotes post-ischemic angiogenesis and recovery, dependent on Pparα, and is elevated in diabetic peripheral arterial disease.

The paper investigates how genetic, epigenetic, and environmental factors influence allele-specific gene expression in mice, identifying tissue- and context-dependent patterns and inconsistent ASE biases.

This study identifies fatty acid synthesis in satellite glial cells as a mechanism promoting axon regeneration after nerve injury.

The paper identifies epistatic gene interactions underlying parent-of-origin effects on metabolic traits in mice using reciprocal crosses and tissue-specific expression analysis.