Murali Cherukuri Krishna

This study shows that improving tumor blood flow enhances the abscopal effect in mice treated with radiation and PD-1 blockade, by increasing immune activation and reducing hypoxia.

This study shows that pharmacological ascorbate induces transient hypoxia in pancreatic ductal adenocarcinoma, enhancing the efficacy of the hypoxia-activated prodrug evofosfamide in some tumor models.