A scalable cell-free manufacturing platform for two-step bioproduction of immunogenic conjugate vaccines
Derek A. Wong, Rochelle Aw, Sophia W. Hulbert, Yufan Sunny Qin, Zachary M. Shaver, Kathryn A. Myers, Ashty S. Karim, Matthew P. DeLisa, Michael C. Jewett
This paper presents a cell-free manufacturing platform for producing conjugate vaccines with high glycosylation efficiency and purity, validated through immunogenicity testing in mice.
ACS Synthetic Biology · Nov 19, 2025Peer-reviewedSynthetic Biology