Qiang Qiu

Persistent Neurological Deficits in Mouse PASC Reveal Antiviral Drug Limitations

This study shows that antiviral drugs fail to prevent neurological deficits in SARS-CoV-2-infected mice, which resemble neurodegenerative diseases due to chronic inflammation.

Spatiotemporal Mapping and Molecular Basis of Whole-brain Circuit Maturation

This study creates DevATLAS to map spatiotemporal circuit maturation in postnatal mouse brains and identifies molecular mechanisms and impairments in neurodevelopmental disorders.

Molecular Control of Circuit Plasticity and the Permanence of Imprinted Odor Memory

The paper identifies Fzd1 as a master regulator of the critical period for olfactory imprinting, showing its role in closing the period to lock in permanent odor memory circuits.

A physicochemical model of odor sampling

The paper develops a physicochemical model of odor sampling that simulates ligand-receptor interactions and evaluates their impact on odor discrimination sensitivity.

Acquisition of Innate Odor Preference Depends on Spontaneous and Experiential Activities During Critical Period

This study shows that innate odor preference in mice requires both spontaneous neural activity and sensory experience during a critical period, with ectopic projections altering odor valence.

Encoding Innately Recognized Odors via a Generalized Population Code

The paper shows that innate odor valence is not encoded through insulated channels but is instead re-coded via crosstalk among mitral/tufted cells in the olfactory bulb, abolishing innate behavioral responses to mixed odors.