Author

Andrew T. Brawner

SUNY Upstate Medical UniversityORCID 0000-0002-7906-727XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. Ron YuiD· 1 shared Haipeng XueiD· 1 shared Hyosung KimiD· 1 shared Jacqueline R. ThompsoniD· 1 shared Jian XueiD· 1 shared Jing-Jing Liu· 1 shared Kyra T. NewmasteriD· 1 shared Peng JiangiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

C. Ron YuORCID

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2 papers

Recent·Most cited

Spatiotemporal Mapping and Molecular Basis of Whole-brain Circuit Maturation

Jian Xue, Andrew T. Brawner, Jacqueline R. Thompson, Tushar Devanand Yelhekar, Kyra T. Newmaster, Qiang Qiu, Yonatan A. Cooper, C. Ron Yu, Yasir H. Ahmed-Braima, Yongsoo Kim, Yingxi Lin

This study creates DevATLAS to map spatiotemporal circuit maturation in postnatal mouse brains and identifies molecular mechanisms and impairments in neurodevelopmental disorders.

bioRxiv · Jan 3, 2024 · PreprintNeuroscience

OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome

Ranjie Xu, Andrew T. Brawner, Shenglan Li, Jing-Jing Liu, Hyosung Kim, Haipeng Xue, Zhiping P. Pang, Woo-Yang Kim, Ronald P. Hart, Ying Liu, Peng Jiang

This study shows that OLIG2 overexpression in Down syndrome patient-derived iPSCs leads to abnormal neurodevelopmental phenotypes, including impaired recognition memory in chimeric mice.

Cell stem cell · May 23, 2019Peer-reviewedNeuroscience