Cancer BiologybioRxivPreprint
Cellular consequences, citrullination substrates, and antigenicity resulting from wild-type and targeted PAD4 on cell surfaces
Sophie Kong, Trenton M. Peters-Clarke, Corleone S. Delaveris…·James A. Wells
This study identifies PAD4 substrates and their citrullination effects, showing PAD4 induces cell migration and generates citrullinated peptides that can trigger autoantibodies.
DOI 10.64898/2026.01.05.696859