Pharmacology & ToxicologyNaturePeer-reviewed
Design of allosteric modulators that change GPCR G protein subtype selectivity
Madelyn N. Moore, Kelsey L. Person, Valeria L. Robleto…·Lauren M. Slosky
This study designs allosteric modulators that alter GPCR G protein subtype selectivity by targeting the receptor-transducer interface, demonstrating predictable mechanisms for rational drug design.
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