C1orf112 is a novel regulator of interstrand crosslink that decreases FIGNL1-RAD51 interaction
Edgar Pinedo Carpio, Julien Dessapt, Romain Villot, Lauralicia Sacre, Abba Malina, Jonathan Boulais, Élise G. Lavoie, Vincent Mingyi Luo, Anna-Maria Lazaratos, Jean‐François Côté, Frédérick A. Mallette, Alba Guarné, Amélie Fradet‐Turcotte, Alexandre Orthwein
The paper identifies C1orf112 as a novel regulator of interstrand crosslinks that decreases FIGNL1-RAD51 interaction, impairing homology-directed repair.
bioRxiv · Oct 6, 2022 · PreprintMolecular Biology