Cell BiologybioRxivPreprint
Targeting the TEA DNA binding Domain of TEAD with a Peptide Inhibitor TEAi Suppresses Oncogenic Transcription and Tumor Growth
Hui Xiong, Ruohui Han, Xiaohui Lin…·Lei Cao
This paper develops TEAi, a peptide inhibitor targeting TEAD's DNA-binding domain, which suppresses TEAD-YAP/TAZ-driven transcription and tumor growth.
DOI 10.1101/2025.08.31.672803