Consensus native-like hepatitis C virus E1E2 engages broadly neutralizing antibody precursors
Fabian Mulder, Fabien Cannac, Joan Capella-Pujol, Stan Peters, Meliawati Poniman, Wouter Olijhoek, Luke A. Granger, Marco Antonio Briones-Orta, Kostas Paschos, Sophie van der Pol, Ruben Walen, Maddy L. Newby, Wen-Hsin Lee, Laura Radić, Ian Zon, , Kwinten Sliepen
This paper develops a consensus HCV E1E2 antigen that engages germline B cell precursors of broadly neutralizing antibodies.
bioRxiv · Aug 26, 2026 · PreprintImmunology