Author

Tessy Korthout

Royal Netherlands Academy of Arts and SciencesORCID 0000-0002-7384-5923Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:spatial domain detection· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Jop KindiD· 2 shared Kim L. de LucaiD· 2 shared Alexander van OudenaardeniD· 1 shared Deepani W. Poramba‐LiyanageiD· 1 shared Frank P. A. van GemertiD· 1 shared Fred van LeeuweniD· 1 shared Hiroshi KimurâiD· 1 shared Ila van Kruijsbergen· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenomics

Jop KindORCID

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3 papers

Recent·Most cited

Time-resolved and multifactorial profiling in single cells resolves the order of heterochromatin formation events during X-chromosome inactivation

Samy Kefalopoulou, Pim M. J. Rullens, Kim L. de Luca, Sandra S. de Vries, Tessy Korthout, Alexander van Oudenaarden, Peter J. Zeller, Jop Kind

The paper introduces Dam&ChIC, a method for time-resolved chromatin profiling in single cells, revealing that genome-lamina detachment precedes H3K27me3 accumulation during X-chromosome inactivation.

Nature Cell Biology · Jul 1, 2025Peer-reviewedGenomics

Combinatorial single-cell profiling of all major chromatin types with MAbID

Silke J. A. Lochs, Robin H. van der Weide, Kim L. de Luca, Tessy Korthout, Ramada E. van Beek, Hiroshi Kimurâ, Jop Kind

MAbID enables simultaneous profiling of multiple chromatin states in single cells, revealing multifactorial chromatin state changes during neural differentiation.

Nature Methods · Dec 4, 2023Peer-reviewedGenomics

Decoding the chromatin proteome of a single genomic locus by DNA sequencing

Tessy Korthout, Deepani W. Poramba‐Liyanage, Ila van Kruijsbergen, Kitty F. Verzijlbergen, Frank P. A. van Gemert, Tibor van Welsem, Fred van Leeuwen

The paper introduces Epi-Decoder, a DNA sequencing-based method to systematically identify and quantify the chromatin proteome of a specific genomic locus in budding yeast, revealing dynamic changes under replication stress.

PLoS Biology · Jul 13, 2018Peer-reviewedGenomics