Author

Pim M. J. Rullens

Royal Netherlands Academy of Arts and SciencesORCID 0009-0007-4176-5674Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Assay:scRNA-seq· 2 Research Focus:spatial domain detection· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jop KindiD· 4 shared Sandra S. de Vries· 3 shared Kim L. de LucaiD· 2 shared Marvin E. TanenbaumiD· 2 shared Silke J. A. LochsiD· 2 shared A. Marieke OudelaariD· 1 shared Agnieszka Gacek‐MatthewsiD· 1 shared Alexander van OudenaardeniD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersGenomics

Jop KindORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 8, 2026

Linking live-cell imaging to single-cell sequencing using genetic barcoding

Micha Muller, Silke J. A. Lochs, Leonie Apperloo…·Marvin E. Tanenbaum

This paper introduces Waldo, a genetic barcoding system that links live-cell imaging phenotypes to single-cell sequencing data for the same cells.

DOI 10.64898/2026.10.07.757257

imagingscRNA-seq

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Molecular BiologybioRxivPreprintSep 1, 2025

MeCP2 binding and genome-lamina reorganization precede long gene activation during mouse corticogenesis

Pim M. J. Rullens, Sandra S. de Vries, Silke J. A. Lochs…·Jop Kind

The paper identifies genome-lamina reorganization preceding long gene activation in mouse corticogenesis and links it to MeCP2 binding.

3 citations

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GenomicsNature Cell BiologyPeer-reviewedJul 1, 2025

Time-resolved and multifactorial profiling in single cells resolves the order of heterochromatin formation events during X-chromosome inactivation

Samy Kefalopoulou, Pim M. J. Rullens, Kim L. de Luca…·Jop Kind

The paper introduces Dam&ChIC, a method for time-resolved chromatin profiling in single cells, revealing that genome-lamina detachment precedes H3K27me3 accumulation during X-chromosome inactivation.

13 citations

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GenomicsbioRxivPreprintMay 10, 2023

Genome-wide profiling of DNA repair proteins identifies higher-order coordination in single cells

Kim L. de Luca, Pim M. J. Rullens, Magdalena A. Karpińska…·Jop Kind

This study identifies higher-order coordination of DNA repair proteins in single cells by analyzing their genome-wide localization using DamID and ChIC sequencing.

3 citations

ChIP-seqexperimental assay

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