Author

Juliana J. Lee

Harvard UniversityORCID 0000-0002-7393-9997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Sina BooeshaghiiD· 1 shared Aaron StreetsiD· 1 shared Adam R. MarksiD· 1 shared Alexander M. TsankoviD· 1 shared Andrew J. KaufmaniD· 1 shared Assaf MageniD· 1 shared Benoit KloeckneriD· 1 shared Brian D. BrowniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

A. Sina BooeshaghiORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 23, 2026

Denoising single-cell ATAC-seq data with Shannon entropy

Shiyi Yang, Kevin An, Juliana J. Lee…·Aaron Streets

This paper introduces a Shannon entropy-based method to filter high-quality nuclei in scATAC-seq data, improving signal-to-noise ratio and downstream analysis reliability.

DOI 10.64898/2026.10.20.760589

scATAC-seqstatistical model

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ImmunologyNaturePeer-reviewedSep 10, 2025

Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors

Samarth Hegde, Bruno Giotti, Brian Y. Soong…·Miriam Mérad

The paper identifies NRF2-driven myeloid progenitor dysregulation that sustains immunosuppressive macrophages in tumors, showing NRF2 inhibition reduces their survival and enhances antitumor immunity.

52 citationstop 1%

mousehuman

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