Jose J. Rosado‐Franco

Primary Human Macrophages Exhibit Functional CYP3A4 Activity with Marked Expression-Function Discordance and Cocaine-Induced Catalytic Activation

This study shows human macrophages have functional CYP3A4 activity, with expression and function discordance, and cocaine increases CYP3A4 activity across donors.

Chronic {triangleup}9-Tetrahydrocannabinol Vapor Self-Administration Modulates Gut Microbiota and the Immune and Endocannabinoid Systems in Female Sprague-Dawley Rats

This study shows chronic THC vapor exposure in rats affects brain endocannabinoid and immune systems but not peripheral organs, leading to gut microbiota changes and altered metabolites.

Antiviral and Anti-inflammatory Effects of Cannabidiol in HIV/SIV Infection

This study shows CBD reduces viral replication and immune activation in HIV/SIV models, suggesting it could be a useful adjunct to antiretroviral therapy.

Deepening biomedical research training: Community-Building Wellness Workshops for Post-Baccalaureate Research Education Program (PREP) Trainees

This paper describes a wellness program for PREP trainees that improved their resilience and skills through community-building workshops and peer mentorship.

Cocaine Regulates Antiretroviral Therapy CNS Access Through Pregnane-X Receptor-Mediated Drug Transporter and Metabolizing Enzyme Modulation at the Blood Brain Barrier

This study investigates how cocaine affects the transport and metabolism of antiretroviral drugs across the blood-brain barrier by modulating drug transporters and enzymes.

Roadmap For The Expression Of Canonical and Extended Endocannabinoid System Receptors and Proteins in Peripheral Organs of Preclinical Animal Models

The paper evaluates gene expression of endocannabinoid receptors across species and organs, revealing limited cross-species overlap and highlighting challenges in translational research.