Author

Lisa B. Fridman

Johns Hopkins UniversityORCID 0009-0002-3873-8206Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A C PriceiD· 1 shared Alex T. LarssoniD· 1 shared Alicia MercadoiD· 1 shared Angela C. HirbeiD· 1 shared Belinda B. GaranaiD· 1 shared Benjamin C. OrsburniD· 1 shared Bianca R. FloresiD· 1 shared Christine A. PratilasiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

A C PriceORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 29, 2026

Integrated ex vivo screening and transcriptomic profiling to prioritize drug combinations for rare cancers

Ritu C. Shah, Alex T. Larsson, Belinda B. Garana…·Sara J.C. Gosline

The paper develops EXACT, a framework combining ex vivo drug screening with transcriptomic analysis to identify effective drug combinations for rare cancers, finding a MEK and HDAC inhibitor combination shows enhanced activity.

DOI 10.64898/2026.07.28.741264

humanbulk RNA-seq

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NeuroscienceFluids and Barriers of the CNSPeer-reviewedJan 10, 2024

Cocaine Regulates Antiretroviral Therapy CNS Access Through Pregnane-X Receptor-Mediated Drug Transporter and Metabolizing Enzyme Modulation at the Blood Brain Barrier

Rodnie Colón Ortiz, Stephen A. Knerler, Lisa B. Fridman…·Dionna W. Williams

This study investigates how cocaine affects the transport and metabolism of antiretroviral drugs across the blood-brain barrier by modulating drug transporters and enzymes.

12 citations

humanexperimental assay

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