Author

Piroska E. Szabó

Van Andel InstituteORCID 0000-0001-9314-7009Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetics· 2 Cell Biology· 1 Developmental Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 6 Research Focus:differential expression· 5 Approach:statistical model· 5 Assay:bulk RNA-seq· 3 Assay:DNA methylation· 3 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Ji LiaoiD· 5 shared Tie-Bo ZengiD· 3 shared Marie AdamsiD· 2 shared Nicholas Pierce· 2 shared Wanding ZhouiD· 2 shared Alexandra VanderArk· 1 shared Artūras PetronisiD· 1 shared Ashley K. WisemaniD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersGenetics

Ji LiaoORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

GeneticsbioRxivPreprintOct 7, 2025

Maternal SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven 2-cell totipotency transcriptional program in the mouse embryo

Tie-Bo Zeng, Zhen Fang Fu, Mary F. Majewski…·Piroska E. Szabó

The paper shows that maternal SETDB1 is essential for silencing 2-cell totipotency genes in mouse embryos, allowing development beyond the 8-cell stage.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintSep 7, 2025

EHMT2 Controls Neural Crest-Derived Craniofacial Development but is Dispensable in Limb Development

Ye Liu, Yaguang Zhao, Minmin Liu…·Tao Yang

This study shows EHMT2 is essential for neural crest-derived craniofacial development but not for limb development.

DOI 10.1101/2025.09.07.674526

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsCell GenomicsPeer-reviewedJul 1, 2022

DNA Methylation Dynamics and Dysregulation Delineated by High-Throughput Profiling in the Mouse

Wanding Zhou, Toshinori Hinoue, Bret Barnes…·Peter W. Laird

This paper develops a high-throughput DNA methylation array and atlas for mice, revealing tissue-specific methylation patterns and their associations with aging, differentiation, and disease.

120 citationstop 1%

mouseDNA methylation

𝕏 PostBluesky

GeneticsEpigenomicsPeer-reviewedAug 1, 2021

H3K9 methyltransferase EHMT2/G9a controls ERVK-driven non-canonical imprinted genes

Tie-Bo Zeng, Nicholas Pierce, Ji Liao, Piroska E. Szabó

The paper shows EHMT2 maintains non-canonical imprinting by repressing ERVK promoters through DNA methylation and H3K4me3.

17 citations

mouseDNA methylation

𝕏 PostBluesky

Developmental BiologybioRxivPreprintMar 29, 2021

EHMT2 Controls Transcriptional Noise and the Developmental Switch after Gastrulation in the Mouse Embryo

Tie-Bo Zeng, Nicholas Pierce, Ji Liao…·Piroska E. Szabó

The paper investigates the role of EHMT2 in transcriptional regulation during mouse embryonic development, finding it controls transcriptional noise and developmental gene switches.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 6, 2018

Differential DNA modification of an enhancer at the IGF2 locus affects dopamine synthesis in patients with major psychosis

Shraddha Pai, Peipei Li, Bryan A. Killinger…·Viviane Labrie

The paper identifies reduced DNA modifications at an IGF2 enhancer in psychosis patients, linking it to disrupted dopamine synthesis in mice.

1 citation

mouseDNA methylation

𝕏 PostBluesky