Author

Michelle L. Dykstra

Van Andel Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Abigail E. EllisiD· 1 shared Evan J. WordeniD· 1 shared Jacob Z. Longenecker· 1 shared Minmin LiuiD· 1 shared Morgan T. Canfield· 1 shared Peter A. JonesiD· 1 shared Pieter R. NordeniD· 1 shared Riley J. WedaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Abigail E. EllisORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cells Engage Endogenous Malonate Synthesis to Drive Mitochondrial Metabolism

Riley J. Wedan, Pieter R. Norden, Morgan T. Canfield, Abigail E. Ellis, Sanskriti Saxena, Jacob Z. Longenecker, Michelle L. Dykstra, Ryan D. Sheldon, Sara M. Nowinski

The paper identifies malonate as an endogenous intermediate supporting mitochondrial fatty acid synthesis and oxidative phosphorylation, showing ACC1-dependent synthesis from glucose.

bioRxiv · May 29, 2026 · PreprintBiochemistry

The structural basis for de novo DNA methylation in chromatin

Xiaoyan Xie, Minmin Liu, X. Edward Zhou, Michelle L. Dykstra, Peter A. Jones, Evan J. Worden

This study reports Cryo-EM structures of DNMT3A2/3B3 bound to di-nucleosomes, revealing how linker length and H3K36 methylation influence DNA methylation.

bioRxiv · Dec 19, 2024 · PreprintBiophysics