MicrobiologyPLoS PathogensPeer-reviewed
Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal
William J. Cisneros, Shimaa Hassan AbdelAziz Soliman, Miriam Walter…·Judd F. Hultquist
This paper shows that inhibiting the Super Elongation Complex (SEC) with KL-2 increases HIV-1 transcription and reactivates latent virus, especially when combined with other latency reversing agents.
6 citations