Author

Wout J. Weuring

University Medical Center UtrechtORCID 0000-0002-7439-5653Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant calling· 1 Organism:zebrafish· 1

Frequent Co-Authors

Bobby P.C. KoelemaniD· 2 shared Els De VriendtiD· 1 shared Irina VetteriD· 1 shared J. van de VondervoortiD· 1 shared Kees P. J. BrauniD· 1 shared Linda VolkersiD· 1 shared M.P. KoetsieriD· 1 shared Marco C. Inserra· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Bobby P.C. KoelemanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Efficient and accurate prime editing strategy to correct genetic alterations in hiPSC using single EF-1alpha driven all-in-one plasmids

Wout J. Weuring, Nina Dirkx, Els De Vriendt, Noor Smal, J. van de Vondervoort, van ’t Ruben Slot, M.P. Koetsier, Sarah Weckhuysen, Bobby P.C. Koeleman

This study develops and tests novel all-in-one plasmids for prime editing in hiPSC, achieving up to 50% edit efficiency with reduced off-target effects.

bioRxiv · May 4, 2022 · PreprintMolecular Biology

NaV1.1 and NaV1.6 selective compounds reduce the behavior phenotype in a novel zebrafish model for Dravet Syndrome

Wout J. Weuring, Sakshi Singh, Linda Volkers, Martin B. Rook, Ruben van ‘t Slot, Marjolein Bosma, Marco C. Inserra, Irina Vetter, Nanda M. Verhoeven‐Duif, Kees P. J. Braun, Mirko Rivara, Bobby P.C. Koeleman

This study develops a zebrafish model for Dravet Syndrome and tests compounds that selectively target Nav1.1 or Nav1.6 channels, showing both reduce seizure-like behavior.

PLoS ONE · Mar 5, 2020Peer-reviewedGenetics