Author

Sebastian Temme

Düsseldorf University HospitalORCID 0000-0002-8807-2767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander LangiD· 1 shared Anja StefanskiiD· 1 shared Christian JungiD· 1 shared Denada ArifajiD· 1 shared Dominik N. MülleriD· 1 shared Georg NickenigiD· 1 shared Guang YangiD· 1 shared Hendrik BartolomaeusiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPhysiology

Alexander LangORCID

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2 papers

Recent·Most cited

Large extracellular vesicles derived from red blood cells in coronary artery disease patients with anemia promote endothelial dysfunction

Isabella Solga, Leon Götzmann, Vithya Yogathasan, Patricia Wischmann, Tin Yau Pang, Patricia Kleimann, Sebastian Temme, Lina Hofer, Anja Stefanski, Alexander Lang, Georg Nickenig, Christian Jung, Norbert Gerdes, Mohammed Rabiul Hosen, Malte Kelm, Ramesh Chennupati

This study shows that anemia in coronary artery disease patients increases release of red blood cell-derived extracellular vesicles (REVs) that promote endothelial dysfunction by enhancing nitric oxide consumption and oxidative stress.

Journal of Molecular and Cellular Cardiology · Jun 26, 2026Peer-reviewedPhysiology

Human T Cells From Resistant Hypertension Patients Promote Hypertension via TNF in humanized mice

Masudur Rahman, Hendrik Bartolomaeus, Lydia Hering, Mina Yakoub, Guang Yang, Johannes Benjamin Holle, Lukas Streese, Denada Arifaj, Milena Hahn, Marta Kantauskaitė, Tim Felix Grüner, Jaroslawna Meister, Nicola Wilck, Markus Kleinewietfeld, Lars Christian Rump, , Johannes Stegbauer

The paper shows that T cells from treatment-resistant hypertension patients worsen hypertension and endothelial dysfunction in humanized mice through TNF.

bioRxiv · Jan 25, 2026 · PreprintImmunology