IFNgamma-dependent remodelling of the myeloid landscape underlies control of IFNgamma-insensitive tumours
Vivian Wing Chong Lau, Gracie J. Mead, Zofia Varyova, Julie M. Mazet, Anagha Yogam Krishnan, Edward W. Roberts, Gennaro Prota, Uzi Gileadi, Kim S. Midwood, Vincenzo Cerundolo, Audrey Gérard
The paper shows that IFN-gamma-insensitive tumours can still be controlled by immune responses, with IFN-gamma driving myeloid cell remodelling that enhances anti-tumour immunity.
Nature Communications · Jan 2, 2025Peer-reviewedImmunology