Author

Sophia M. Carlin

University of PittsburghORCID 0000-0002-7455-5127Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Approach:genetic perturbation / CRISPR· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Gideon H. HillebrandiD· 4 shared Elizabeth J. GiacobeiD· 3 shared Thomas Alexander HooveniD· 3 shared A Peters· 1 shared Austin S NeeliD· 1 shared C Nichols· 1 shared David Michael AronoffiD· 1 shared Devin L. Stauff· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

Gideon H. HillebrandORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 16, 2026

The bacterial cell membrane acts as a dynamic heme reservoir during group B Streptococcus bloodstream infection

Gideon H. Hillebrand, Heather A Stephenson, Elizabeth J. Giacobe…·Thomas Alexander Hooven

DOI 10.64898/2026.05.15.725516

humanexperimental assay

𝕏 PostBluesky

MicrobiologyMolecular MicrobiologyPeer-reviewedSep 13, 2025

A Cas12a Toolbox for Rapid and Flexible Group B Streptococcus Genomic Editing and CRISPRi

Gideon H. Hillebrand, Sophia M. Carlin, Elizabeth J. Giacobe…·Thomas Alexander Hooven

This paper develops a Cas12a-based toolkit for efficient genomic editing and CRISPRi in Group B Streptococcus, enabling targeted gene modifications and inducible gene silencing with minimal off-target effects.

5 citations

experimental assaygenetic perturbation / CRISPR

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedMay 23, 2025

FapR regulates HssRS-mediated heme homeostasis in Bacillus anthracis

Hualiang Pi, Owen S. Burroughs, Sophia M. Carlin…·Eric Patrick Skaar

This study identifies FapR as a regulator of HssRS-mediated heme homeostasis in B. anthracis, showing its role in maintaining membrane integrity and HssS localization.

2 citations

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologyInfection and ImmunityPeer-reviewedMar 21, 2025

A CRISPRi Library Screen in Group B Streptococcus Identifies Surface Immunogenic Protein (Sip) as a Mediator of Multiple Host Interactions

Kyle Firestone, Kathyayini P. Gopalakrishna, Lisa M. Rogers…·Thomas Alexander Hooven

This study uses CRISPRi to identify Sip as a key surface protein in GBS that modulates host interactions and pathogenesis.

1 citation

virusgenetic perturbation / CRISPR

𝕏 PostBluesky