Author

Marius Marc-Daniel Mader

Institute for Stem Cell Biology and Regenerative MedicineORCID 0000-0002-7467-9672Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Marius WernigiD· 2 shared Micaiah AtkinsiD· 2 shared Oliver HahniD· 2 shared Yohei ShibuyaiD· 2 shared Yongjin YooiD· 2 shared Agnieszka A. WendorffiD· 1 shared Alan NapoleiD· 1 shared Alexa ScavettiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Marius WernigORCID

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Author profile →

2 papers

Recent·Most cited

Heterochronic myeloid cell replacement reveals the local brain environment as key driver of microglia aging

Claire Gizowski, Galina Popova, Heather Shin, Marius Marc-Daniel Mader, Wendy Craft, Wenjun Kong, Yohei Shibuya, Bernd J. Wranik, Yan Hong Huang Fu, Constanze Depp, Tzu‐Hua Lin, Baby Martin-McNulty, Yongjin Yoo, Po-Han Tai, Maximilian Hingerl, , Oliver Hahn

This study uses heterochronic myeloid cell replacement to show that the local brain environment, not intrinsic factors, drives microglia aging.

bioRxiv · Sep 2, 2025 · PreprintNeuroscience

Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation

Marius Marc-Daniel Mader, Alan Napole, Danwei Wu, Micaiah Atkins, Alexa Scavetti, Yohei Shibuya, Aulden G. Foltz, Oliver Hahn, Yongjin Yoo, Ron Danziger, Christina Tan, Tony Wyss‐Coray, Lawrence Steinman, Marius Wernig

This study identifies a neuroprotective myeloid state in MS and EAE models, showing that HCT enhances this state, leading to clinical improvement and reduced demyelination.

Nature Neuroscience · Mar 21, 2024Peer-reviewedNeuroscience