Author

Ganesh A. Thakur

Northeastern UniversityORCID 0000-0002-7468-8819Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Animal Behavior & Cognition· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Lucas Cantwell· 3 shared Andrea G. HohmanniD· 2 shared Abhijit KulkarniiD· 1 shared Ana Santa‐CruziD· 1 shared Andrew Zorn· 1 shared Diomedes E. LogothetisiD· 1 shared Emily Fender SizemoreiD· 1 shared Evangelos DadiotisiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersPharmacology & Toxicology

Lucas Cantwell

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 16, 2026

GAT1508, a selective neuronal GIRK1/2 activator, exhibits superior antiepileptic efficacy and synergizes with cannabidiol

Jahnavi Simhadri, Andrew Zorn, Liang Wang…·Stelios M. Smirnakis

This study characterizes GAT1508, a selective neuronal GIRK1/2 activator, showing superior antiepileptic efficacy and synergy with CBD.

DOI 10.64898/2026.10.14.758970

mouseelectronic health records

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Animal Behavior & CognitionAddiction BiologyPeer-reviewedAug 1, 2024

Negative allosteric modulation of CB1 cannabinoid receptor signaling decreases intravenous morphine self-administration and relapse in mice

Idaira Oliva, Fezaan Kazi, Lucas Cantwell…·Andrea G. Hohmann

This study shows that negative allosteric modulation of CB1 receptors reduces morphine self-administration and relapse in mice without affecting food reward motivation.

7 citations

mouseexperimental assay

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NeurosciencebioRxivPreprintJan 6, 2024

Negative allosteric modulation of cannabinoid CB1 receptor signaling suppresses opioid-mediated tolerance and withdrawal without blocking opioid antinociception

Vishakh Iyer, Shahin A. Saberi, Romario Pacheco…·Andrea G. Hohmann

This study shows that the CB1 receptor NAM GAT358 reduces opioid tolerance and withdrawal without impairing analgesia in mice.

2 citations

mouseexperimental assay

𝕏 PostBluesky