Andrea G. Hohmann

This study shows acetaminophen reduces pain by altering lipid signaling via cannabinoid receptors and enzymes in mice.

This study shows CBD reduces chemotherapy-induced neuropathic pain through NAPE-PLD and PPAR receptor pathways, but not CB1/CB2.

This study evaluates the effects of LY2828360, a CB2 agonist, on evoked and spontaneous pain in a rat spared nerve injury model, finding robust suppression of evoked pain but variable results for spontaneous pain assessed via CPP.

This study shows that xylazine worsens fentanyl-induced respiratory depression and prevents naloxone reversal, but can be counteracted by combining naloxone with atipamezole in mice.

This study evaluates CB2-specific antibody agonists for treating chemotherapy-induced peripheral neuropathy, showing pain relief without tolerance or off-target effects.

This study investigates the role of NAPE-PLD in opioid responsiveness and finds sex-dependent differences in oxycodone and sucrose consumption in knockout mice.

This paper evaluates (S)-MeCPP-115, a novel GABA-AT inactivator, showing it reduces paclitaxel-induced neuropathic pain in mice without affecting paclitaxel's cytotoxicity or causing significant toxicity.

This study shows that mild traumatic brain injury impairs episodic memory in rats using a human-like task, without affecting non-episodic memory.

This study shows that mild traumatic brain injury impairs spatial working memory in rats using an animal model.

This study shows that CB1 agonists like CP55,940 and THC cause respiratory depression in awake mice, contradicting previous beliefs about their minimal respiratory impact.

This study identifies multiple molecular mechanisms by which velvet ant venom activates nociceptors in both vertebrates and invertebrates.

This study shows that genetic deletion of NAPE-PLD in mice leads to anxiety-like behaviors and context-dependent dysregulation of the HPA axis, with sex-specific effects on corticosterone levels.

This study shows that negative allosteric modulation of CB1 receptors reduces morphine self-administration and relapse in mice without affecting food reward motivation.

This study identifies primary sensory neurons as the cell type mediating anti-allodynic effects of CB2 agonists and reveals a sexually dimorphic sparing of morphine tolerance in male mice.

This study shows that the CB1 receptor NAM GAT358 reduces opioid tolerance and withdrawal without impairing analgesia in mice.

This study shows that CB2 receptors in peripheral sensory neurons are essential for the antinociceptive effects of CB2 agonists and their ability to reverse morphine tolerance in a neuropathic pain model.