Author

Michael B. Wheeler

University of TorontoORCID 0000-0002-7480-7267Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andreea ObersterescuiD· 1 shared Babak RazaniiD· 1 shared Bradly G. WoutersiD· 1 shared Brian CoxiD· 1 shared Curtis M. WoodfordiD· 1 shared Erica P. GundersoniD· 1 shared Haneesha MohaniD· 1 shared Huntley H. ChangiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Andreea ObersterescuORCID

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2 papers

Recent·Most cited

metGWAS 1.0: An R workflow for network-driven over-representation analysis between independent metabolomic and meta-genome wide association studies

Saifur Rahman Khan, Andreea Obersterescu, Erica P. Gunderson, Babak Razani, Michael B. Wheeler, Brian Cox

metGWAS 1.0 statically evaluates independent metabolomics and GWAS studies to identify novel metabolite-gene associations using hypergeometric testing.

Bioinformatics · Aug 23, 2023Peer-reviewedBioinformatics

Nicotinamide promotes differentiation of pancreatic endocrine progenitors from human pluripotent stem cells through poly (ADP-ribose) polymerase inhibition

Curtis M. Woodford, Ting Yin, Huntley H. Chang, Romario Regeenes, Ravi Nagaraj Vellanki, Haneesha Mohan, Bradly G. Wouters, Jonathan V. Rocheleau, Michael B. Wheeler, Peter W. Zandstra

This paper shows nicotinamide promotes pancreatic endocrine progenitor differentiation via PARP inhibition, increasing Nkx6.1 and NAD+/NADH ratio.

bioRxiv · Apr 21, 2020 · PreprintDevelopmental Biology