Developmental BiologybioRxivPreprint
Nicotinamide promotes differentiation of pancreatic endocrine progenitors from human pluripotent stem cells through poly (ADP-ribose) polymerase inhibition
Curtis M. Woodford, Ting Yin, Huntley H. Chang…·Peter W. Zandstra
This paper shows nicotinamide promotes pancreatic endocrine progenitor differentiation via PARP inhibition, increasing Nkx6.1 and NAD+/NADH ratio.