Author

Curtis M. Woodford

University of TorontoORCID 0000-0002-6955-8155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Peter W. ZandstraiD· 2 shared Alice VickersiD· 1 shared Blaise LouisiD· 1 shared Bradly G. WoutersiD· 1 shared Daniel Aguilar‐HidalgoiD· 1 shared David Becerra‐AlonsoiD· 1 shared Davide DanoviiD· 1 shared Dominika DziedzickaiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

Peter W. ZandstraORCID

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2 papers

Recent·Most cited

Nicotinamide promotes differentiation of pancreatic endocrine progenitors from human pluripotent stem cells through poly (ADP-ribose) polymerase inhibition

Curtis M. Woodford, Ting Yin, Huntley H. Chang, Romario Regeenes, Ravi Nagaraj Vellanki, Haneesha Mohan, Bradly G. Wouters, Jonathan V. Rocheleau, Michael B. Wheeler, Peter W. Zandstra

This paper shows nicotinamide promotes pancreatic endocrine progenitor differentiation via PARP inhibition, increasing Nkx6.1 and NAD+/NADH ratio.

bioRxiv · Apr 21, 2020 · PreprintDevelopmental Biology

High-throughput micro-patterning platform reveals Nodal-dependent dissection of peri-gastrulation-associated versus pre-neurulation associated fate patterning

Mukul Tewary, Dominika Dziedzicka, Joel Östblom, Laura Prochazka, Nika Shakiba, Tiam Heydari, Daniel Aguilar‐Hidalgo, Curtis M. Woodford, Elia Piccinini, David Becerra‐Alonso, Alice Vickers, Blaise Louis, Nafees Rahman, Davide Danovi, Mieke Geens, , Peter W. Zandstra

The paper develops an in vitro platform to study fate patterning in hPSCs, revealing Nodal-dependent switches between gastrulation and neurulation-associated gene profiles.

PLoS Biology · Oct 21, 2019Peer-reviewedDevelopmental Biology