Author

Cesar M. Castro

Harvard UniversityORCID 0000-0002-7527-2233Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Bo R. RuedaiD· 1 shared Cheng WangiD· 1 shared Chisa ShimadaiD· 1 shared Dominique T. ZarrellaiD· 1 shared Eugene KimiD· 1 shared Hyungsoon ImiD· 1 shared Karen D. Cowden DahliD· 1 shared Kenneth P. NephewiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Bo R. RuedaORCID

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1 paper

Recent·Most cited

Extracellular vesicles facilitate the horizontal transfer of drug resistance and stem-like properties between ovarian tumor cells

Venkatesh Pooladanda, Rui Fang Xu, Dominique T. Zarrella, Yusuke Matoba, Chisa Shimada, Shaan Kumar, Eugene Kim, Paula J DiBenedetto, Xingping Qin, Kristopher A. Sarosiek, Madelyn Krueger, Narela Magrassi, Mansoor M. Amiji, Maryam Azimi Mohammadabadi, Ursula Winter, , Bo R. Rueda

This study shows that extracellular vesicles from ovarian cancer stem cells or drug-resistant cells transfer stem-like properties and drug resistance to sensitive cells via EZH2 signaling.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology