Author

Venkatesh Pooladanda

Harvard UniversityORCID 0000-0002-2506-011XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bo R. RuedaiD· 3 shared Eugene KimiD· 2 shared Shaan KumariD· 2 shared Abby E. Smith· 1 shared Adriaan F. Hubertus de Groot· 1 shared Alexander Daniel CarliniD· 1 shared Anil Kumar KalvalaiD· 1 shared Anthony P. PossematoiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

Bo R. RuedaORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 23, 2026

Extracellular vesicles facilitate the horizontal transfer of drug resistance and stem-like properties between ovarian tumor cells

Venkatesh Pooladanda, Rui Fang Xu, Dominique T. Zarrella…·Bo R. Rueda

This study shows that extracellular vesicles from ovarian cancer stem cells or drug-resistant cells transfer stem-like properties and drug resistance to sensitive cells via EZH2 signaling.

1 citation

humanorganoid / primary culture

𝕏 PostBluesky

Cancer BiologyCommunications BiologyPeer-reviewedNov 20, 2025

Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes.

Anil Kumar Kalvala, Ashok Silwal, Bhaumik B. Patel…·Magdalena Karbowniczek

This study shows that extracellular vesicles from LAM cells promote metastasis by delivering ATP to pseudopodia and activating integrin adhesion complexes.

4 citations

humanexperimental assay

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Molecular BiologybioRxivPreprintMar 11, 2023

Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway

Junbing Zhang, Claire M. Simpson, Jacqueline Berner…·Liron Bar‐Peled

The paper identifies a nucleus-to-mitochondria ROS sensing pathway involving CHK1 and SSBP1 that mediates resistance to platinum-based chemotherapies in ovarian cancers.

DOI 10.1101/2023.03.11.532189

humanproteomics

𝕏 PostBluesky