Author

Caleb A. Stine

Virginia TechORCID 0000-0002-7540-9316Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Cora EsparzaiD· 2 shared Jennifer M. MunsoniD· 2 shared Jessica J. CunninghamiD· 2 shared Kathryn M. KingsmoreiD· 2 shared Maosen WangiD· 2 shared Aizhen Xiao· 1 shared Alexis Petrosky· 1 shared Austin Hoggarth· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Cora EsparzaORCID

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2 papers

Recent·Most cited

S1PR3 mediates glial stimulated tumor invasion in response to interstitial fluid flow

R. Chase Cornelison, Samantha Howerton, Kinsley M. Tate, Caleb A. Stine, Alexis Petrosky, Kathryn M. Kingsmore, Sharon K. Michelhaugh, Jessica J. Cunningham, Katie Degen, Austin Hoggarth, Cora Esparza, Peng Jin, Maosen Wang, Caroline O’Brien, Aizhen Xiao, , Jennifer M. Munson

This study shows interstitial fluid flow upregulates S1PR3 in glial cells, promoting glioma invasion, and demonstrates that targeting S1PR3 can limit tumor progression.

bioRxiv · Dec 3, 2025 · PreprintCancer Biology

Interstitial fluid transport dynamics predict glioblastoma invasion and progression

Cora Esparza, Caleb A. Stine, Naciye Atay, Kathryn M. Kingsmore, Maosen Wang, Ryan T. Woodall, Russell C. Rockne, Jessica J. Cunningham, Jennifer M. Munson

The paper uses MRI to predict glioblastoma invasion and progression by analyzing interstitial fluid flow patterns.

npj Biomedical Innovations. · Sep 3, 2025Peer-reviewedBioengineering