Elias M. Wisdom

The paper engineers an electrical synapse in mice using fish connexins to modulate neural circuits and behavior.

The paper shows that electrical synapses in C. elegans filter sensory information to guide context-specific behavioral choices by modulating neuronal excitability and integration of temperature stimuli.

The paper develops engineered gap junction hemichannels to enable precise, long-term neural circuit editing in mammals by enabling communication between distinct cell types.