Author

Paddy S. Gibson

University of LausanneORCID 0000-0002-7563-9824Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jan‐Willem VeeningiD· 3 shared Afonso Martins BravoiD· 2 shared Axel B. JansseniD· 2 shared Vincent de BakkeriD· 2 shared Alexandra StreamiD· 1 shared Andrew VarbleiD· 1 shared Bevika SewgoolamiD· 1 shared Elisabet BjånesiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

Jan‐Willem VeeningORCID

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3 papers

Recent·Most cited

Genome-wide antibiotic-CRISPRi profiling identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae

Bevika Sewgoolam, Kin Ki Jim, Vincent de Bakker, Florian Patrick Bock, Paddy S. Gibson, Jan‐Willem Veening

The paper identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae using CRISPRi-seq and antibiotic combination therapy.

Nature Communications · Jul 14, 2025Peer-reviewedMicrobiology

PneumoBrowse 2: An integrated visual platform for curated genome annotation and multiomics data analysis of Streptococcus pneumoniae

Axel B. Janssen, Paddy S. Gibson, Afonso Martins Bravo, Vincent de Bakker, Jelle Slager, Jan‐Willem Veening

PneumoBrowse 2 provides an updated integrated platform for genome annotation and multi-omics data analysis of Streptococcus pneumoniae, enhancing research into its biology and potential treatments.

Nucleic Acids Research · Oct 4, 2024Peer-reviewedMicrobiology

An efficient in vivo-inducible CRISPR interference system for group A Streptococcus genetic analysis and pathogenesis studies

Elisabet Bjånes, Alexandra Stream, Axel B. Janssen, Paddy S. Gibson, Afonso Martins Bravo, Samira Dahesh, Jonathon L. Baker, Andrew Varble, Victor Nizet, Jan‐Willem Veening

This paper develops a doxycycline-inducible CRISPRi system for GAS to enable efficient gene repression and presents a genome browser for GAS genetic features.

mBio · Jul 2, 2024Peer-reviewedMicrobiology