Author

Bevika Sewgoolam

University of LausanneORCID 0009-0002-0797-0686Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jan‐Willem VeeningiD· 2 shared Vincent de BakkeriD· 2 shared Amelieke J. H. CremersiD· 1 shared Axel B. JansseniD· 1 shared Babet Rozendal· 1 shared Florian Patrick BockiD· 1 shared Kin Ki JimiD· 1 shared Louise MartiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Jan‐Willem VeeningORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A functional genetic landscape of antibiotic sensitivity across the pneumococcal pangenome reveals conserved and lineage-specific vulnerabilities

Bevika Sewgoolam, Axel B. Janssen, Louise Martin, Rengifo-Gonzalez Monica, Vincent de Bakker, Babet Rozendal, Amelieke J. H. Cremers, Jan‐Willem Veening

This study uses CRISPRi-seq to identify genes affecting antibiotic sensitivity across diverse pneumococcal strains, revealing conserved and lineage-specific vulnerabilities.

bioRxiv · Feb 26, 2026 · PreprintMicrobiology

Genome-wide antibiotic-CRISPRi profiling identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae

Bevika Sewgoolam, Kin Ki Jim, Vincent de Bakker, Florian Patrick Bock, Paddy S. Gibson, Jan‐Willem Veening

The paper identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae using CRISPRi-seq and antibiotic combination therapy.

Nature Communications · Jul 14, 2025Peer-reviewedMicrobiology