Author

Carson C. Cole

Rice UniversityORCID 0000-0002-7573-1882Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Brett H. PogostiniD· 3 shared Jeffrey D. HartgerinkiD· 3 shared Joseph W. R. SwainiD· 3 shared Adam C. FarsheediD· 2 shared Anatoly B. KolomeiskyiD· 2 shared Jonathan T. MakhouliD· 2 shared Kiana A. CahueiD· 2 shared Marija DubackiciD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

Brett H. PogostinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Supramolecular assembly of collagen mimetic peptide D-periodic fibrils and nanoassemblies

Carson C. Cole, Mark A. B. Kreutzberger, Kevin Klein, Kiana A. Cahue, Brett H. Pogostin, Adam C. Farsheed, Joseph W. R. Swain, Thi H. Bui, Arghadip Dey, Jonathan T. Makhoul, Marija Dubackic, Antara Pal, Ulf Olsson, Anđela Šarić, Edward H. Egelman, Jeffrey D. Hartgerink

This study investigates how interhelical interactions guide the assembly of collagen mimetic peptides into D-periodic fibrils, nanotubes, and nanosheets.

Biomacromolecules · Mar 26, 2026Peer-reviewedBiochemistry

Covalent Stabilization of Collagen Mimetic Triple Helices and Assemblies by Dopa Crosslinking

Carson C. Cole, Brett H. Pogostin, Kiana A. Cahue, Vardan Hoviki Vardanyan, Thi H. Bui, Adam C. Farsheed, Joseph W. R. Swain, Jonathan T. Makhoul, Marija Dubackic, Peter Holmqvist, Ulf Olsson, Anatoly B. Kolomeisky, Kevin J. McHugh, Jeffrey D. Hartgerink

This paper demonstrates that Dopa crosslinking with lysine covalently stabilizes collagen mimetic peptides and their assemblies, enhancing thermal stability for biomedical applications.

ChemBioChem · Jul 3, 2025Peer-reviewedBiochemistry

Heterotrimeric Collagen Helix with High Specificity of Assembly Results in a Rapid Rate of Folding

Carson C. Cole, Douglas R. Walker, Sarah A. H. Hulgan, Brett H. Pogostin, Joseph W. R. Swain, Mitchell D. Miller, Weijun Xu, Ryan Duella, Mikita M. Misiura, Xu Wang, Anatoly B. Kolomeisky, George N. Phillips Jr, Jeffrey D. Hartgerink

This paper designs a collagen heterotrimer with high folding specificity and reports its faster folding rate compared to other systems.

Nature Chemistry · Jul 15, 2024Peer-reviewedBiophysics