Anatoly B. Kolomeisky

This study develops a theoretical framework to quantify how reversible mRNA condensation affects transcriptional noise and robustness.

This paper presents a stochastic model to study microbial growth dynamics in a single-species-single-resource system, identifying three dynamical regimes and showing how stochasticity affects behavior at low population levels.

The paper proposes a stochastic mechanism for dominant follicle selection, showing how FSH and estradiol interact to ensure single follicle selection through negative feedback.

The paper develops a physical-chemical framework to identify fragment-level structural determinants of molecular mechanisms, applying it to pyronaridine's crystal-growth inhibition and antimalarial activity.

The paper demonstrates that the Fano factor can be used to determine cooperativity in biological networks, showing that non-linear Fano factor variation indicates positive cooperativity.

This study develops a theoretical model to explain sequence-dependent transcriptional error rates, revealing how downstream nucleotides influence RNA polymerase II fidelity.

This paper demonstrates that Dopa crosslinking with lysine covalently stabilizes collagen mimetic peptides and their assemblies, enhancing thermal stability for biomedical applications.

This study shows that feature selection improves peptide binding predictions for TCRs by optimizing model complexity and performance using physicochemical properties and machine learning.

This study improves T cell-antigen specificity prediction by integrating kinetic data into affinity-driven models, enhancing predictions for low-affinity TCR-pMHC interactions.

This paper designs a collagen heterotrimer with high folding specificity and reports its faster folding rate compared to other systems.

The paper develops a computational method to predict protein-protein interactions using dipeptide compositions as key features, showing strong correlation across organisms.

The paper develops a molecular model explaining how surface interactions accelerate protein aggregation, validated through experiments with synuclein and APOBEC3G.