Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells
Yanling Huang, Haocong Mo, Jie Yang, Luyang Gao, Tian Tao, Qing Shu, Wenying Guo, Yawen Zhao, Jingya Lyu, Qimeng Wang, Jinghui Guo, Hening Zhai, Linyan Zhu, Hui Chen, Geyang Xu
This study shows that Piezo1 in intestinal L cells mechanically regulates GLP-1 production, affecting glucose tolerance and diabetes.
eLife · Jun 19, 2024Peer-reviewedPhysiology