Author

Alexander C. Monovich

University of MichiganORCID 0000-0002-7589-1026Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Russell J.H. RyaniD· 2 shared Brennan P. BergeroniD· 1 shared Charles Grenfell MullighaniD· 1 shared Ching‐Hon PuiiD· 1 shared Christopher S. ManringiD· 1 shared Colton Dysart· 1 shared Connor G Burke· 1 shared Dahlya Kamarudin· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Russell J.H. RyanORCID

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Author profile →

2 papers

Recent·Most cited

EZH2-driven immune evasion at disease presentation defines atargetable high-risk subset of acute leukemia exemplified byt(16;21) FUS::ERG AML

Nathaniel J. Buteyn, Samantha J LaMantia, Connor G Burke, Vincent J Sartori, Yizhou Peter Huang, Colton Dysart, Eve Deering-Gardner, Zachary J. DeBruine, Dahlya Kamarudin, Darrell P. Chandler, Alexander C. Monovich, Monika W. Perez, Joanna S. Yi, Rhonda E. Ries, Todd A. Alonzo, , Timothy Junius Triche

This paper identifies an EZH2-driven immune evasion phenotype in FUS::ERG AML that is reversible with tazemetostat, offering a potential targeted therapy for high-risk acute leukemia.

Blood Neoplasia · Sep 1, 2026Peer-reviewedCancer Biology

Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures

Kelly R. Barnett, Robert J. Mobley, Jonathan D. Diedrich, Brennan P. Bergeron, Kashi Raj Bhattarai, Alexander C. Monovich, Shilpa Narina, Wenjian Yang, Kristine R. Crews, Christopher S. Manring, Elias Joseph Jabbour, Elisabeth M. Paietta, Mark Robert Litzow, Steven Mitchell Kornblau, Wendy Stock, , Daniel Savic

The paper maps chromatin accessibility in B-ALL subtypes using ATAC-seq, identifies TFs and genetic variants influencing chromatin architecture and gene regulation.

Cell Genomics · Nov 20, 2023Peer-reviewedGenomics