ER-to-Golgi Trafficking is a Nutrient-Sensitive Checkpoint Linking Glucose Starvation to Cell Surface Remodeling
Joung Hyuck Joo, William Kasberg, Spencer Douglas, Uwemedimo G. Udoh, Alexandre F. Carisey, James Messing, Yong‐Dong Wang, Shilpa Narina, Shondra M. Pruett‐Miller, Myriam Labelle, Jennifer Lippincott‐Schwartz, Chi‐Lun Chang, Mondira Kundu
The paper shows glucose starvation impairs ER-to-Golgi trafficking, reducing surface proteins like E-cadherin and promoting metastasis through AMPK and ULK1 signaling.
bioRxiv · Oct 31, 2025 · PreprintCell Biology