Author

Mhairi Copland

University of GlasgowORCID 0000-0002-7655-016XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alex TonksiD· 1 shared Amy Lianne MuiriD· 1 shared Benjamin P. TowleriD· 1 shared David A. PalmeriD· 1 shared Dennis Famili· 1 shared Dominic R. M. Meek· 1 shared Elif Nehir Bayat· 1 shared Ewan A. RossiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Alex TonksORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

RUNX1 aberrations in blast-phase CML induce the RBP SPATS2L which promotes growth, survival and stress granule assembly

David A. Palmer, Amy Lianne Muir, R Craig, Philip A. Lewis, Marieangela C. Wilson, Kate J. Heesom, Gillian Abigail Horne, Mhairi Copland, Satu M. Mustjoki, Shady Adnan Awad, Kimmo Porkka, Sanjana Jain, Elif Nehir Bayat, Dennis Famili, Helen Webb, , Rhys G Morgan

This study identifies SPATS2L as a mediator of growth and survival in RUNX1-mutant blast-phase CML through stress granule formation, suggesting it as a therapeutic target.

bioRxiv · Mar 30, 2026 · PreprintCancer Biology

Bioengineered bone marrows that can support stem cells and remodel to mimic human disease metabolism and chemotherapeutic effects

Yinbo Xiao, Savvas Ioannou, Monica P. Tsimbouri, Xiang Li, Oana Dobre, Sara Trujillo, Mark Robert Sprott, Mariana Azevedo Gonzalez‐Oliva, Vineetha Jayawarna, Massimo Vassalli, Ewan A. Ross, Mhairi Copland, Peter S. Young, Dominic R. M. Meek, Manuel Salmerón‐Sánchez, , Matthew John Dalby

The paper develops a bioengineered bone marrow model that supports stem cells and mimics disease metabolism and chemotherapy effects, showing enhanced taurine metabolism and chemotherapy response.

bioRxiv · Dec 5, 2025 · PreprintBioengineering