Carolina B. López

RIG-I-MAVS-NOXA axis coordinates antiviral defense and apoptosis during parahenipavirus infection

This study identifies a RIG-I-MAVS-IFN-NOXA signaling axis that coordinates antiviral defense and apoptosis during GAKV infection.

Circadian Clock Gene Modulation and Selective Reprogramming in Response to Virus Infection

This study shows that viral replication byproducts called cbVGs drive changes in circadian gene expression during infection through distinct immune pathways, with ARNTL2 playing a key role in amplifying antiviral responses.

Detailed single-cell mapping of the transcriptional response to a virus infection driven by copy-back viral genomes

The paper uses single-cell RNA-sequencing to study how copy-back viral genomes drive host cell responses during Sendai virus infection, revealing dynamic transcriptional changes over time.

Terminal Loop Sequences in Viral Double-Stranded RNAs Modulate RIG-I Signaling

The paper shows that terminal loop sequences in viral double-stranded RNAs enhance RIG-I signaling and IFN expression, with synthetic versions triggering innate immune responses in mice.

Variable and conserved features of copy-back viral genome populations generated de novo during Sendai virus infection

This study investigates copy-back viral genomes (cbVGs) generated during Sendai virus infection, finding conserved and variable features in their generation and accumulation across different viral stocks.

A chronic murine model of pulmonary Acinetobacter baumannii infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections

Validation of diverse and previously untraceable Sendai virus copyback viral genomes by Direct RNA Sequencing

The paper optimizes Direct RNA Sequencing to obtain full-length copyback viral genomes and introduces a BLAST-based tool for their detection.

Detection and characterization of Langya virus in Crocidura lasiura, Republic of Korea

This study identifies Langya virus Korea (LayV KOR) in shrews in South Korea, showing 80% and 95.5% homology to the Chinese strain at nucleotide and amino acid levels.

SLC35A2 modulates paramyxovirus fusion events during infection

This study identifies SLC35A2 as a host factor essential for paramyxovirus fusion during infection, showing its role in virus-cell and cell-to-cell fusion events.

DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge

This paper tests DDO268 as an adjuvant for an influenza A virus nucleoprotein mRNA vaccine in mice, showing enhanced immune responses and protection against viral challenge.

Identification of distinct genotypes in circulating RSV A strains based on variants on the virus replication-associated genes

The paper identifies distinct genotypes in RSV A strains by analyzing variants in replication-associated genes from sequenced samples and highlights the polymerase protein L as a robust genotyping target.

VODKA2: A fast and accurate method to detect non-standard viral genomes from large RNA-seq datasets

VODKA2 detects non-standard viral genomes from RNA-seq data using an HPC-optimized pipeline.