Deepika Puri

This study investigates the relationship between age-related epigenetic changes in DNA methylation, chromatin accessibility, and histone modifications across human aging using integrated WGBS and ATAC-seq data.

This study uses multimodal single-cell analysis to identify transcription factor networks involved in T-cell aging.

This study shows that protamine overexpression in somatic cells causes chromatin condensation and transcription suppression without altering DNA methylation.

This study shows NSD1 regulates DNA methylation and endodermal differentiation of human iPSCs through HIDEN lncRNA, revealing a novel mechanism linked to Sotos syndrome.

This study identifies FOXD3 as a regulator of repeat element transcription in mouse embryonic stem cells, showing it represses 2-cell state genes and repeat sequences by promoting heterochromatin formation.