Author

Mara Steiger

Hasso Plattner InstituteORCID 0000-0002-3747-685XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:ATAC-seq· 3 Research Focus:differential expression· 3 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:experimental assay· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Alexander MeissneriD· 3 shared Helene KretzmeriD· 3 shared Deepika PuriiD· 2 shared Giulia Fornero· 2 shared Hannes KlumpiD· 2 shared Ivan G. CostaiD· 2 shared Mina ShaiganiD· 2 shared René KrügeriD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersGenomics

Alexander MeissnerORCID

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Author profile →

4 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 27, 2026

Genome-wide multi-layered epigenomic profiling across human aging

Mara Steiger, René Krüger, Mina Shaigan…·Wolfgang Wagner

This study investigates the relationship between age-related epigenetic changes in DNA methylation, chromatin accessibility, and histone modifications across human aging using integrated WGBS and ATAC-seq data.

DOI 10.64898/2026.07.27.740934

humanDNA methylation

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BioinformaticsbioRxivPreprintMay 21, 2026

Multimodal single-cell analysis uncovers transcription factor networks underlying T-cell aging

Mina Shaigan, Deepika Puri, Giulia Fornero…·Ivan G. Costa

This study uses multimodal single-cell analysis to identify transcription factor networks involved in T-cell aging.

DOI 10.64898/2026.05.19.726137

humanscRNA-seq

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NeurosciencebioRxivPreprintOct 1, 2025

Human brain organoids record the passage of time over multiple years in culture

Irene Faravelli, Noelia Antón-Bolaños, Anqi Wei…·Paola Arlotta

This study shows human brain organoids can mature over 5 years in culture, transcriptionally aging and retaining memory of time spent in vitro.

14 citations

humanbulk RNA-seq

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GenomicsNucleic Acids ResearchPeer-reviewedOct 22, 2021

Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq

Laura V. Glaser, Mara Steiger, Alisa Fuchs…·Sebastiaan H. Meijsing

The paper quantifies enhancer activity dynamics in mESCs during differentiation using FAIRE-STARR-seq, identifying features that predict enhancer activity and reveal regulatory insights.

15 citations

mouseATAC-seq

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