Author

Daniel Newhouse

East Carolina UniversityORCID 0000-0002-7694-0475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Organism:zebrafish· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Christopher N. BalakrishnaniD· 2 shared Andrea N. SelsethiD· 1 shared Barbara K. FelberiD· 1 shared Bryan E. RandalliD· 1 shared Colette M. Hughes· 1 shared Connor B. Driscoll· 1 shared Daniella DeWeerdiD· 1 shared David MorrowiD· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersGenomics

Christopher N. BalakrishnanORCID

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4 papers

Recent·Most cited

Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology

Thomas M. Goralski, Lindsay K. Meyerdirk, Libby Breton, Laura Brasseur, Kevin Kurgat, Daniella DeWeerd, Lisa Turner, Katelyn Becker, Marie Adams, Daniel Newhouse, Michael X. Henderson

The paper uses spatial transcriptomics to identify specific cortical neurons vulnerable to Lewy pathology in PD and discovers a conserved molecular dysfunction signature in both mice and humans.

Nature Communications · Mar 26, 2024Peer-reviewedNeuroscience

Sustained IL-15 response signature predicts RhCMV/SIV vaccine efficacy

Fredrik Barrenäs, Scott G. Hansen, G. Lynn Law, Connor B. Driscoll, Richard R. Green, Elise A. Smith, Jean Chang, Inah Golez, Taryn Urion, Xinxia Peng, Leanne S. Whitmore, Daniel Newhouse, Colette M. Hughes, David Morrow, Kurt T. Randall, , Michael Gale

The paper identifies an IL-15 response signature in vaccinated rhesus macaques that correlates with protection against SIV challenge following RhCMV/SIV vaccination.

bioRxiv · Jan 11, 2021 · PreprintGenomics

Parent and offspring genotypes influence gene expression in early life

Daniel Newhouse, Margarida Barcelo‐Serra, Elaina M. Tuttle, Rusty A. Gonser, Christopher N. Balakrishnan

The paper examines how parental genotypes and care strategies affect nestling gene expression in white-throated sparrows, identifying differentially expressed genes and co-expression modules linked to metabolism and stress response.

Molecular Ecology · Aug 17, 2019Peer-reviewedGenomics

Transcriptional response to West Nile virus infection in the zebra finch (Taeniopygia guttata), a songbird model for immune function

Daniel Newhouse, Erik K. Hofmeister, Christopher N. Balakrishnan

This study investigates the transcriptional response to West Nile virus infection in zebra finches, identifying similarities and differences with mammalian immune responses.

Royal Society Open Science · Jun 1, 2017Peer-reviewedGenomics