Álvaro F. Fernández

Au_Sus provides a high-confidence human autophagy gene census through consensus of databases and literature, revealing a core 201-gene set with significant associations to neurodegeneration and oncology.

This study shows that ATG4D deficiency in mice causes late-onset cardiomyopathy and stress-induced heart failure, and ATG4D repression is linked to human cardiac remodeling.

This study shows that loss of ATG4B, ATG4C, and ATG4D in mice causes systemic autophagy defects, leading to accelerated aging and shortened lifespan.

This study examines how different exercise protocols affect autophagy in white and brown adipose tissues of mice, revealing protocol- and tissue-specific changes in autophagy markers.