Isaac Tamargo‐Gómez

ATG4D loss leads to late-onset cardiomyopathy and stress-induced heart failure in mice, and its repression marks maladaptive cardiac remodeling in humans

This study shows that ATG4D deficiency in mice causes late-onset cardiomyopathy and stress-induced heart failure, and ATG4D repression is linked to human cardiac remodeling.

Combined loss of ATG4B, ATG4C and ATG4D impairs systemic autophagy and triggers accelerated aging in mice

This study shows that loss of ATG4B, ATG4C, and ATG4D in mice causes systemic autophagy defects, leading to accelerated aging and shortened lifespan.

Autophagy alterations in white and brown adipose tissues of mice exercised under different training protocols

This study examines how different exercise protocols affect autophagy in white and brown adipose tissues of mice, revealing protocol- and tissue-specific changes in autophagy markers.