Author

Tomasz Dobrzycki

John Radcliffe HospitalORCID 0000-0002-7708-3188Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:zebrafish· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Mónika Krecsmarik· 2 shared Roger K. PatientiD· 2 shared Rui M. MonteiroiD· 2 shared Bakhta FedlaouiiD· 1 shared Cansu KoyunlariD· 1 shared Christopher B. MahonyiD· 1 shared Emma de PateriD· 1 shared Florian BonkhoferiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersDevelopmental Biology

Mónika Krecsmarik

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2 papers

Recent·Most cited

Deletion of a conserved zebrafish Gata2 enhancer impairs haemogenic endothelium programming and adult haematopoiesis

Tomasz Dobrzycki, Christopher B. Mahony, Mónika Krecsmarik, Cansu Koyunlar, Rossella Rispoli, Joke Zink, Kirsten J. Gussinklo, Bakhta Fedlaoui, Emma de Pater, Roger K. Patient, Rui M. Monteiro

This study shows that deleting a conserved zebrafish Gata2 enhancer impairs haemogenic endothelium programming and adult haematopoiesis, leading to bone marrow failure and immune defects.

bioRxiv · Dec 10, 2019 · PreprintDevelopmental Biology

An optimized pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridization

Tomasz Dobrzycki, Mónika Krecsmarik, Florian Bonkhofer, Roger K. Patient, Rui M. Monteiro

The paper describes an optimized pipeline for genotyping zebrafish embryos after in situ hybridization and digitally quantifying gene expression, improving accuracy and reducing bias.

Biology Open · Jan 1, 2018Peer-reviewedDevelopmental Biology